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Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.005

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_111119846	8.437	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr12_+_79625538	7.589	NM_002469	MYF6	myogenic factor 6 (herculin)
chr10_+_69539255	7.498	NM_032578	MYPN	myopalladin
chr4_+_169654742	6.542	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr5_+_155686333	6.418	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr10_-_75085754	6.003	NM_001114133	SYNPO2L	synaptopodin 2-like
chrX_-_21686079	5.810	NM_014332	SMPX	small muscle protein, X-linked
chr2_+_88148413	5.539	NM_198274	SMYD1	SET and MYND domain containing 1
chr10_-_75080784	4.893	NM_024875	SYNPO2L	synaptopodin 2-like
chr2_+_170074457	4.863	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr8_+_67201684	4.834	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr7_-_41709191	4.650	NM_002192	INHBA	inhibin, beta A
chr15_-_68781662	4.616	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr10_+_50177192	4.276	NM_001135196 NM_199459	C10orf71	chromosome 10 open reading frame 71
chr2_-_190635566	4.233	NM_005259	MSTN	myostatin
chr5_+_53787187	4.219	NM_006308	HSPB3	heat shock 27kDa protein 3
chr16_+_31132842	4.187	NM_001008274	TRIM72	tripartite motif containing 72
chr7_+_93862137	3.922		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr6_-_139654807	3.832	NM_153235	TXLNB	taxilin beta
chr3_-_39209075	3.797	NM_194293 NM_001198621	XIRP1	xin actin-binding repeat containing 1
chr1_-_199657468	3.721	NM_003281	TNNI1	troponin I type 1 (skeletal, slow)
chr11_-_85107569	3.707	NM_206929	SYTL2	synaptotagmin-like 2
chr22_+_24468168	3.701		MYO18B	myosin XVIIIB
chr2_-_162808123	3.693	NM_004460	FAP	fibroblast activation protein, alpha
chr2_-_105421661	3.588	NM_201557	FHL2	four and a half LIM domains 2
chr12_-_55931172	3.572	NM_145064	STAC3	SH3 and cysteine rich domain 3
chr22_+_24468110	3.393	NM_032608	MYO18B	myosin XVIIIB
chr1_-_199613406	3.293		TNNT2	troponin T type 2 (cardiac)
chr1_-_199613427	3.233	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chrX_-_77801480	3.163	NM_152694	ZCCHC5	zinc finger, CCHC domain containing 5
chr10_-_69095362	3.015	NM_001127384	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr2_+_238712101	3.010	NM_198582	KLHL30	kelch-like 30 (Drosophila)
chr3_-_102194938	2.868	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr9_+_96806235	2.821		C9orf3	chromosome 9 open reading frame 3
chr10_+_111755715	2.796	NM_019903	ADD3	adducin 3 (gamma)
chr8_-_122722674	2.776	NM_005328	HAS2	hyaluronan synthase 2
chr3_-_115825742	2.755	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chrX_-_142549984	2.731	NM_001184750	SLITRK4	SLIT and NTRK-like family, member 4
chr4_+_120276386	2.678	NM_016599	MYOZ2	myozenin 2
chr20_+_19903778	2.660		RIN2	Ras and Rab interactor 2
chr3_+_8750485	2.648	NM_033337 NM_001234	CAV3	caveolin 3
chr2_-_179623030	2.606	NM_173648	CCDC141	coiled-coil domain containing 141
chr16_+_14187965	2.586		MKL2	MKL/myocardin-like 2
chr12_+_118100977	2.523	NM_014365	HSPB8	heat shock 22kDa protein 8
chr10_-_95231933	2.488	NM_013451 NM_133337	MYOF	myoferlin
chr7_+_18501876	2.482	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr3_-_11585264	2.348	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr8_-_72431274	2.340	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr2_-_189752575	2.306	NM_000393	COL5A2	collagen, type V, alpha 2
chr3_+_139550368	2.306		MRAS	muscle RAS oncogene homolog
chr5_-_83052606	2.227	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr17_-_10265991	2.190	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr10_+_80569464	2.189		ZMIZ1	zinc finger, MIZ-type containing 1
chr4_-_186934059	2.127	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr3_+_35696119	2.103	NM_001025068 NM_001025069	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr3_+_35658852	2.089	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr6_-_76259976	2.066	NM_015687	FILIP1	filamin A interacting protein 1
chrX_+_152699616	2.059	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr8_-_49996353	2.023	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr14_+_23670514	2.011	NM_203402	FITM1	fat storage-inducing transmembrane protein 1
chr14_+_99309688	2.003		EML1	echinoderm microtubule associated protein like 1
chr3_+_139550134	1.992	NM_001085049	MRAS	muscle RAS oncogene homolog
chr19_+_23091616	1.929		ZNF730	zinc finger protein 730
chr10_+_86174665	1.923		FAM190B	family with sequence similarity 190, member B
chr11_+_5667494	1.911	NM_006074	TRIM22	tripartite motif containing 22
chr1_-_229071957	1.871	NM_001136494	C1orf198	chromosome 1 open reading frame 198
chr4_-_177427252	1.821	NM_080874	ASB5	ankyrin repeat and SOCS box containing 5
chr4_+_169789327	1.813	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr1_-_116112684	1.742		CASQ2	calsequestrin 2 (cardiac muscle)
chr4_+_146820805	1.741	NM_001080531	C4orf51	chromosome 4 open reading frame 51
chr7_+_154943466	1.725	NM_001427	EN2	engrailed homeobox 2
chr7_+_18502342	1.662	NM_058176 NM_178425	HDAC9	histone deacetylase 9
chr6_-_130224108	1.642	NM_001010876	C6orf191	chromosome 6 open reading frame 191
chr1_-_31618405	1.632	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr1_-_85816520	1.626	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_+_144124547	1.624	NM_145277 NM_202004 NM_213652 NM_213653	HFE2	hemochromatosis type 2 (juvenile)
chr1_-_16217025	1.619		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr11_+_5667392	1.605		TRIM22	tripartite motif containing 22
chr21_-_35174742	1.603		RUNX1	runt-related transcription factor 1
chr5_-_142057692	1.595	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr21_+_29439768	1.578		C21orf7	chromosome 21 open reading frame 7
chr1_-_116112853	1.570		CASQ2	calsequestrin 2 (cardiac muscle)
chr2_-_165768798	1.569	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr8_+_107807415	1.559	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chrX_-_142550535	1.553	NM_173078	SLITRK4	SLIT and NTRK-like family, member 4
chr15_+_76345577	1.550	NM_001130183	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_28415495	1.549		LOC401317	hypothetical LOC401317
chr3_+_190147633	1.546		TPRG1	tumor protein p63 regulated 1
chr6_+_136214495	1.541	NM_018945	PDE7B	phosphodiesterase 7B
chr11_+_35922106	1.537	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr20_+_60558104	1.524	NM_178463	C20orf166	chromosome 20 open reading frame 166
chr2_+_233099113	1.522	NM_000751	CHRND	cholinergic receptor, nicotinic, delta
chr3_-_113842652	1.514	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr10_+_70172257	1.506		CCAR1	cell division cycle and apoptosis regulator 1
chr10_-_62373828	1.505	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr3_-_113842553	1.505		CCDC80	coiled-coil domain containing 80
chr17_+_39603599	1.483	NM_080863	ASB16	ankyrin repeat and SOCS box containing 16
chr11_-_19180092	1.482	NM_001127656 NM_003476	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr2_-_210876560	1.473	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr18_+_12397894	1.460	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr17_+_65677255	1.457	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_61676604	1.435	NM_203373	FBXL22	F-box and leucine-rich repeat protein 22
chr17_+_42641712	1.432	NM_002476	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr8_+_70541412	1.426	NM_001128204 NM_015170	SULF1	sulfatase 1
chr2_+_149603226	1.418	NM_177964	LYPD6B	LY6/PLAUR domain containing 6B
chr12_-_68379331	1.414	NM_032735	BEST3	bestrophin 3
chr3_+_50291521	1.401	NM_153215	C3orf45	chromosome 3 open reading frame 45
chr16_-_31347151	1.399	NM_005205	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr1_-_151784889	1.389	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr12_-_21985433	1.387		ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_+_201182187	1.376		AOX1	aldehyde oxidase 1
chr3_+_100840129	1.356	NM_001850 NM_020351	COL8A1	collagen, type VIII, alpha 1
chr11_+_1897374	1.348	NM_001042780 NM_001042781 NM_001042782 NM_006757	TNNT3	troponin T type 3 (skeletal, fast)
chr1_+_158352143	1.342	NM_000702	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr12_-_16650687	1.331		LMO3	LIM domain only 3 (rhombotin-like 2)
chr22_-_28972683	1.330	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr17_-_10362583	1.327	NM_005963	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr10_+_88418243	1.325	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr10_-_92671005	1.319	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr1_-_116112921	1.315	NM_001232	CASQ2	calsequestrin 2 (cardiac muscle)
chr19_+_43847049	1.297
chr6_+_42896771	1.296	NM_015349	KIAA0240	KIAA0240
chr1_+_201364050	1.291		ADORA1	adenosine A1 receptor
chr2_+_102744921	1.282	NM_144632	TMEM182	transmembrane protein 182
chr1_+_25629968	1.254	NM_018202	TMEM57	transmembrane protein 57
chr1_+_12325632	1.249		VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_-_154727014	1.245		MEF2D	myocyte enhancer factor 2D
chr19_-_20540380	1.239	NM_001159293	ZNF737	zinc finger protein 737
chr10_+_91082218	1.219	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chrX_+_70438352	1.191	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr1_-_115039614	1.172	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr12_-_16650697	1.172	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr13_-_59223074	1.150
chr17_-_24491521	1.149		MYO18A	myosin XVIIIA
chr1_+_242283129	1.148	NM_006352	ZNF238	zinc finger protein 238
chr2_+_220007943	1.144	NM_005876	SPEG	SPEG complex locus
chr3_+_185300660	1.142	NM_182589	HTR3E	5-hydroxytryptamine (serotonin) receptor 3, family member E
chr10_-_69125932	1.130	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr10_-_121592020	1.124		MCMBP	minichromosome maintenance complex binding protein
chr4_-_23500706	1.121	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr3_-_139317140	1.115	NM_173543	DZIP1L	DAZ interacting protein 1-like
chr1_+_78243181	1.114	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr12_-_49689295	1.108	NM_001174130	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr18_-_3209986	1.094	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr9_+_115367122	1.088	NM_134427	RGS3	regulator of G-protein signaling 3
chr14_-_88090641	1.087	NM_007039	PTPN21	protein tyrosine phosphatase, non-receptor type 21
chr5_-_140875591	1.081		DIAPH1	diaphanous homolog 1 (Drosophila)
chr4_-_138673078	1.071	NM_019035	PCDH18	protocadherin 18
chr4_+_86918870	1.069	NM_001042669	ARHGAP24	Rho GTPase activating protein 24
chr3_+_8518539	1.068		LMCD1	LIM and cysteine-rich domains 1
chr3_+_137224266	1.058	NM_181897	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_129950222	1.054	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr1_+_144236346	1.047	NM_003637	ITGA10	integrin, alpha 10
chr2_-_151052391	1.045	NM_005168	RND3	Rho family GTPase 3
chr1_+_26220852	1.045	NM_004455	EXTL1	exostoses (multiple)-like 1
chr5_+_121493113	1.044	NM_207317	ZNF474	zinc finger protein 474
chr1_+_144236398	1.041		ITGA10	integrin, alpha 10
chr13_-_97916768	1.040		STK24	serine/threonine kinase 24
chr3_-_147361465	1.027		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr17_+_42641426	1.026	NM_001002841	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr9_+_115396020	1.025	NM_144489	RGS3	regulator of G-protein signaling 3
chr11_+_64838882	1.023	NM_006779	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2
chr4_-_143987053	1.022	NM_001101669 NM_003866	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr14_+_95792299	1.014	NM_000710	BDKRB1	bradykinin receptor B1
chr5_+_92944680	1.012	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr6_+_131613196	1.008	NM_004842 NM_138633	AKAP7	A kinase (PRKA) anchor protein 7
chr6_-_131333173	1.001		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr12_-_49689255	0.999		SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_26220895	0.998		EXTL1	exostoses (multiple)-like 1
chr1_-_202595666	0.994	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr10_+_88418147	0.984	NM_001171610	LDB3	LIM domain binding 3
chr10_+_5478521	0.972	NM_005863	NET1	neuroepithelial cell transforming 1
chr20_+_11846536	0.944	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr19_+_4983899	0.942
chr4_+_114190233	0.918	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr11_-_62213577	0.908		LRRN4CL	LRRN4 C-terminal like
chr11_+_1816808	0.895	NM_003282	TNNI2	troponin I type 2 (skeletal, fast)
chr4_+_86918882	0.891		ARHGAP24	Rho GTPase activating protein 24
chr12_+_15590811	0.888		PTPRO	protein tyrosine phosphatase, receptor type, O
chr11_-_62213946	0.885	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr2_+_5750229	0.882	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chrX_-_11194015	0.880	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr5_+_140730014	0.879	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr3_-_55489973	0.870		WNT5A	wingless-type MMTV integration site family, member 5A
chr11_+_65023218	0.870
chr17_-_26672757	0.865	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr12_+_119224506	0.862	NM_012240	SIRT4	sirtuin 4
chr11_+_65023038	0.861		MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr7_+_30917939	0.859	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr8_+_70541631	0.857		SULF1	sulfatase 1
chr3_+_8518508	0.852	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr8_-_62764839	0.848	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr9_-_14769530	0.845	NM_001177704	FREM1	FRAS1 related extracellular matrix 1
chr8_+_17866373	0.845		PCM1	pericentriolar material 1
chr4_-_5881271	0.834		CRMP1	collapsin response mediator protein 1
chr12_-_242255	0.831	NM_001190997 NM_016615	SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr9_+_70161634	0.828	NM_021965	PGM5	phosphoglucomutase 5
chr4_+_41057322	0.827		LIMCH1	LIM and calponin homology domains 1
chr10_+_91142301	0.826	NM_001548	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr6_-_50039776	0.825	NM_001037499	DEFB114	defensin, beta 114

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.70	2.40e-06	GO:0061061	muscle structure development
3.07	9.24e-06	GO:0003012	muscle system process
2.95	1.57e-05	GO:0007517	muscle organ development
2.75	2.27e-03	GO:0006936	muscle contraction
4.61	3.32e-02	GO:0006941	striated muscle contraction
4.61	3.32e-02	GO:0030049	muscle filament sliding
4.61	3.32e-02	GO:0033275	actin-myosin filament sliding
2.71	4.12e-02	GO:0042692	muscle cell differentiation
4.49	4.40e-02	GO:0070252	actin-mediated cell contraction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.95	3.59e-14	GO:0030016	myofibril
4.80	4.61e-14	GO:0043292	contractile fiber
4.95	9.76e-14	GO:0044449	contractile fiber part
5.07	2.01e-12	GO:0030017	sarcomere
5.50	1.16e-06	GO:0031674	I band
5.72	1.59e-05	GO:0030018	Z disc
6.04	2.74e-02	GO:0032982	myosin filament
7.16	2.92e-02	GO:0031672	A band

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.97	3.49e-02	GO:0008307	structural constituent of muscle